Luvesilocin (RE104) | 5-HT2A agonist | Probechem Biochemicals

Chemical Structure : RE104

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RE104 (Luvesilocin, RE-104)

货号: PC-22530Not For Human Use, Lab Use Only.

Luvesilocin (RE104) is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.

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生物&药学活性

Luvesilocin (RE104) is the prodrug of 4-OH-DiPT, a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM.
A single dose of RE104 (1 mg/kg) significantly reduced mean immobility time at 1 week compared with vehicle (P < 0.001), confirming translational antidepressant potential.

物理化学性质&存储条件

分子量	374.48
分子式	C21H30N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((3-(2-(diisopropylamino)ethyl)-1H-indol-4-yl)oxy)-5-oxopentanoic acid

参考文献

1. Bryson N, et al. ACS Chem Neurosci. 2024 May 17. doi: 10.1021/acschemneuro.4c00058.

RE104 (Luvesilocin, RE-104)

生物&药学活性

物理化学性质&存储条件

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RE104 (Luvesilocin, RE-104)

生物&药学活性

物理化学性质&存储条件

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