RC-106 | Sigma receptor modulator | Probechem Biochemicals

Chemical Structure : RC-106

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RC-106 (RC-106 hydrochloride, RC-106 HCL)

货号: PC-26651Not For Human Use, Lab Use Only.

RC-106 is a high affinity, brain-penetrant, pan-sigma receptor modulator with Ki of 12.0 nM and 22.0 nM for S1R and S2R respectively.

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250 mg		Get quote

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生物&药学活性

RC-106 is a high affinity, brain-penetrant, pan-sigma receptor modulator with Ki of 12.0 nM and 22.0 nM for S1R and S2R respectively.
RC-106 induces a decrease of cell viability in a panel of cancer cell lines (LNCaP, PC3, U87, Paca3, Capan-2, MDA MB 231, SUM 159) expressing both S1R and S2R.
RC-106 (10 uM) induces significant apoptosis in PaCa3 cells, which is caspase-dependent.

物理化学性质&存储条件

分子量	391.98
分子式	C26H30ClN
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Piperidine, 1-[(2E)-3-(2-naphthalenyl)-2-buten-1-yl]-4-(phenylmethyl)-, hydrochloride (1:1)

参考文献

1. Rui M, et al. Eur J Med Chem. 2016 Nov 29;124:649-665.

2. Marino N, et al. Eur J Pharm Sci. 2026 Mar 29:107519.

RC-106 (RC-106 hydrochloride, RC-106 HCL)

生物&药学活性

物理化学性质&存储条件

参考文献

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RC-106 (RC-106 hydrochloride, RC-106 HCL)

生物&药学活性

物理化学性质&存储条件

参考文献

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