RANKL inhibitor T8

Chemical Structure : RANKL inhibitor T8

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货号: PC-25329Not For Human Use, Lab Use Only.

RANKL inhibitor T8 is a nonpeptidic small molecular inhibitor targeting RANKL and RANK protein interaction, directly binds to RANKL with KD of 6.3 uM.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

RANKL inhibitor T8 is a nonpeptidic small molecular inhibitor targeting RANKL and RANK protein interaction, directly binds to RANKL with KD of 6.3 uM.

物理化学性质&存储条件

分子量	623.07
分子式	C26H22ClF3N6O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-((2-(4-chlorobenzoyl)hydrazineyl)(pyrrolidin-1-yl)methylene)-4-(5-(thiophen-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide

参考文献

1. Melagraki G, et al. PLoS Comput Biol. 2017 Apr 20;13(4):e1005372.