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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Interleukin Receptor-R805
R805

Chemical Structure : R805

CAS No.: 457940-87-3

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R805 (R 805)

货号: PC-20490Not For Human Use, Lab Use Only.

R805 is a small molecule modulator of gp130 receptor pro-inflammatory signaling, targets a signaling tyrosine 814 (Y814) within gp130, modulates gp130 Y814 upstream of the SRC and MAPK circuit, elicits a protective effect on tissues after injury.

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10 mg ￥2980 In stock
25 mg ￥4880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

R805 is a small molecule modulator of gp130 receptor pro-inflammatory signaling, targets a signaling tyrosine 814 (Y814) within gp130, modulates gp130 Y814 upstream of the SRC and MAPK circuit, elicits a protective effect on tissues after injury.

物理化学性质&存储条件

分子量 295.36
分子式 C16H13N3OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(4-(p-tolyl)thiazol-2-yl)picolinamide

参考文献

1. Ruzanna Shkhyan, et al. Sci Transl Med. 2023 Mar 22;15(688):eabq2395.

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