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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-Pioglitazone
Pioglitazone

Chemical Structure : Pioglitazone

CAS No.: 111025-46-8

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Pioglitazone (U-72107, U72107)

货号: PC-26222Not For Human Use, Lab Use Only.

Pioglitazone (U 72107) is an orally active and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively, highly selective over PPARα and PPARδ

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50 mg ￥880 In stock
100 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pioglitazone (U 72107) is an orally active and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively, highly selective over PPARα and PPARδ

物理化学性质&存储条件

分子量 356.44
分子式 C19H20N2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione

参考文献

1. Kubota N, et al. J Biol Chem. 2006 Mar 31;281(13):8748-55.

2. Puddu A, et al. Regul Pept. 2012 Aug 20;177(1-3):79-84.

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