Pimelic Diphenylamide 106 |CAS:937039-45-7 Probechem Biochemicals

Chemical Structure : Pimelic Diphenylamide 106

CAS No.: 937039-45-7

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Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657)

货号: PC-45618Not For Human Use, Lab Use Only.

Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657) is a slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively).

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10 mg	￥880	In stock
25 mg	￥1380	In stock
50 mg	￥2180	In stock
100 mg		Get quote

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生物&药学活性

Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657) is a slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively).
Pimelic Diphenylamide 106 shows weak inhibition on HDAC8 (IC50=5 uM).
Pimelic Diphenylamide 106 has preference toward HDAC3.

物理化学性质&存储条件

分子量	339.4314
分子式	C20H25N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 25 mg/mL
Chemical Name/SMILES	Heptanediamide, N1-(2-aminophenyl)-N7-(4-methylphenyl)-

参考文献

1. Chou CJ, et al. J Biol Chem. 2008 Dec 19;283(51):35402-9.

2. Xu C, et al. Chem Biol. 2009 Sep 25;16(9):980-9.

Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657)

生物&药学活性

物理化学性质&存储条件

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Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657)

生物&药学活性

物理化学性质&存储条件

参考文献

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