Pimecrolimus | Calcineurin inhibitor | Probechem Biochemicals

Chemical Structure : Pimecrolimus

CAS No.: 137071-32-0

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货号: PC-26136Not For Human Use, Lab Use Only.

Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with Ki of 117 nM, shows anti-inflammatory activity.

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Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with Ki of 117 nM, shows anti-inflammatory activity.

分子量	810.46
分子式	C43H68ClNO11
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-3-[(1E)-2-[(1R,3R,4S)-4-Chloro-3-methoxycyclohexyl]-1-methylethenyl]-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyr

1. Grassberger M, et al. Br J Dermatol. 1999 Aug;141(2):264-73.

2. Bochelen D, et al. J Pharmacol Exp Ther. 1999 Feb;288(2):653-9.