欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-Piclamilast
Piclamilast

Chemical Structure : Piclamilast

CAS No.: 144035-83-6

加入收藏

Piclamilast (RP-73401, RP73401)

货号: PC-63089Not For Human Use, Lab Use Only.

Piclamilast (RP73401) is a potent and highly selective PDE4 inhibitor with IC50 of 1.2 nM.

规格 价格 库存 数量
5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Piclamilast (RP73401) is a potent and highly selective PDE4 inhibitor with IC50 of 1.2 nM.
Piclamilast displays >19,000-fold selectivity for PDE4 compared to other PDE isoenzymes.
Piclamilast shows anti-inflammatory and bronchodilator properties in guinea-pig and rat models of bronchoconstriction and allergic inflammation.

物理化学性质&存储条件

分子量 381.253
分子式 C18H18Cl2N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-benzamide

参考文献

1. Ashton MJ, et al. J Med Chem. 1994 May 27;37(11):1696-703.

2. Raeburn D, et al. Br J Pharmacol. 1994 Dec;113(4):1423-31.

3. Souness JE, et al. Br J Pharmacol. 1995 May;115(1):39-46.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: