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首页-抗体和重组蛋白-Biosimilar Antibody-Palivizumab
Palivizumab

Chemical Structure : Palivizumab

CAS No.: 188039-54-5

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Palivizumab (Anti-human RSV-F mAb, human IgG1-Kappa; MEDI-493)

货号: PC-Ab1100Not For Human Use, Lab Use Only.

Palivizumab (MEDI-493) is a monoclonal antibody to the RSV F protein that inhibits binding of the virus to cellular receptors. This reduces viral activity and cell-to-cell transmission, and blocks the fusion of infected cells. Palivizumab is directed at an epitope in the A antigenic site of the 'F' protein on the surface of RSV. Palivizumab binds to this epitope, which is highly conserved among different RSV isolates..

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5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Palivizumab (MEDI-493) is a monoclonal antibody to the RSV F protein that inhibits binding of the virus to cellular receptors. This reduces viral activity and cell-to-cell transmission, and blocks the fusion of infected cells. Palivizumab is directed at an epitope in the A antigenic site of the 'F' protein on the surface of RSV. Palivizumab binds to this epitope, which is highly conserved among different RSV isolates.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Palivizumab; Synagis; MEDI-493; 188039-54-5; Anti-RSV fusion protein; Anti-RSV fusion glycoprotein; Anti respiratory syncytial virus fusion protein; Anti-RSV fusion

参考文献

1. 1, Johnson S, et al. J Infect Dis. 1997 Nov;176(5):1215-24.  2, Malley R, et al. J Infect Dis. 1998 Dec;178(6):1555-61.  3, Johnson S, et al. J Infect Dis. 1999 Jul;180(1):35-40. 4, Russell AB. Hosp Med. 1999 Dec;60(12):873-7.

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