Pactamycin |CAS: 23668-11-3 Probechem Biochemicals

Chemical Structure : Pactamycin

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Pactamycin (NSC 52947)

货号: PC-62849Not For Human Use, Lab Use Only.

Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial activity.

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生物&药学活性

Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial activity.

物理化学性质&存储条件

分子量	558.62
分子式	C28H38N4O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[(1S,2R,3R,4S,5S)-5-(3-acetylanilino)-4-amino-3-(dimethylcarbamoylamino)-1,2-dihydroxy-3-[(1S)-1-hydroxyethyl]-2-methylcyclopentyl]methyl 2-hydroxy-6-methylbenzoate

参考文献

1. Bhuyan BK. Biochem Pharmacol. 1967 Aug;16(8):1411-20.

2. Suzuki H, et al. Proc Natl Acad Sci U S A. 1974 Oct;71(10):4259-63.

3. Kappen LS, et al. Biochemistry. 1976 Feb 24;15(4):811-8.

4. Hanessian S, et al. Bioorg Med Chem. 2013 Apr 1;21(7):1775-86.

Pactamycin (NSC 52947)

生物&药学活性

物理化学性质&存储条件

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Pactamycin (NSC 52947)

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物理化学性质&存储条件

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