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Paclitaxel

Chemical Structure : Paclitaxel

CAS No.: 33069-62-4

Paclitaxel

货号: PC-25975Not For Human Use, Lab Use Only.

Paclitaxel is a naturally occurring antineoplastic agent and tubulin polymerization stabilizer, induces both mitotic arrest and apoptotic cell death, also induces autophagy.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Paclitaxel is a naturally occurring antineoplastic agent and tubulin polymerization stabilizer, induces both mitotic arrest and apoptotic cell death, also induces autophagy.

物理化学性质&存储条件

分子量 853.91
分子式 C47H51NO14
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b-diyl diacetate

参考文献

1. Choi YH, et al. Oncol Rep. 2012 Dec;28(6):2163-9.

2. Dziadyk JM, et al. Anticancer Res. 2004 Jan-Feb;24(1):27-36.

3. Pan Z, et al. Biochem Biophys Res Commun. 2013 Feb 13. pii: S0006-291X(13)00259-3.

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