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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-PZ-II-029
PZ-II-029

Chemical Structure : PZ-II-029

CAS No.: 164025-44-9

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PZ-II-029

货号: PC-25018Not For Human Use, Lab Use Only.

PZ-II-029 is a selective, positive allosteric modulator (PAM) of α6 subunit-containing GABAA receptor, potentiates α6β3γ2S GABAA receptor‐mediated GABA currents.

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5 mg ￥980 In stock
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25 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PZ-II-029 is a selective, positive allosteric modulator (PAM) of α6 subunit-containing GABAA receptor, potentiates α6β3γ2S GABAA receptor‐mediated GABA currents.

物理化学性质&存储条件

分子量 321.34
分子式 C18H15N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-Methoxy-2-(4-methoxyphenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one

参考文献

1. Fan PC, et al. Neuropharmacology. 2018 Sep 15;140:1-13.

2. Chiou LC, et al. Br J Pharmacol. 2018 Jun;175(12):2414-2427.

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