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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-PU-HZ151
PU-HZ151

Chemical Structure : PU-HZ151

CAS No.: 1000999-96-1

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PU-HZ151 (Icapamespib, PU HZ151)

货号: PC-72711Not For Human Use, Lab Use Only.

PU-HZ151 (Icapamespib, PU HZ151) is a specific CNS-directed epichaperome probe, with selectivity for epichaperomes over the individual chaperome membersm, inhibits HSP90 with EC50 of 5 nM in the FP assays.

规格 价格 库存 数量
2 mg ￥1880 In stock
5 mg ￥3280 In stock
10 mg ￥5280 In stock
25 mg ￥8980 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: 99.5% (HPLC) Select Batch:

生物&药学活性

PU-HZ151 (Icapamespib, PU HZ151) is a specific CNS-directed epichaperome probe, with selectivity for epichaperomes over the individual chaperome membersm, inhibits HSP90 with EC50 of 5 nM in the FP assays.

物理化学性质&存储条件

分子量 526.398
分子式 C19H23IN6O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine

参考文献

1. Bolaender A, et al. Nat Commun. 2021 Aug 3;12(1):4669.

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