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首页-抗体药物偶连体和PROTACs-E3 Ligase Ligand-PT-179
PT-179

Chemical Structure : PT-179

CAS No.: 2924858-25-1

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PT-179 (PT179)

货号: PC-21965Not For Human Use, Lab Use Only.

PT-179 is a selective molecular glue and thalidomide derivative, binds CRBN with a Kd of 587 nM, does not induce degradation of known pomalidomide neosubstrates.

规格 价格 库存 数量
5 mg ￥580 In stock
10 mg ￥880 In stock
25 mg ￥1580 In stock
50 mg ￥2480 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: 99.9% (HPLC) Select Batch:

生物&药学活性

PT-179 is a selective molecular glue and thalidomide derivative, binds CRBN with a Kd of 587 nM, does not induce degradation of known pomalidomide neosubstrates.

物理化学性质&存储条件

分子量 343.34
分子式 C17H17N3O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2,6-dioxopiperidin-3-yl)-5-morpholinoisoindoline-1,3-dione

参考文献

1. Mercer JAM, et al. Science. 2024 Mar 15;383(6688):eadk4422.

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