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首页-小分子抑制剂&激动剂-GPCR-GPR84-PSB-16434
PSB-16434

Chemical Structure : PSB-16434

CAS No.: 2189700-02-3

PSB-16434 (PSB16434)

货号: PC-21649Not For Human Use, Lab Use Only.

PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.
    PSB-16434 shows selectivity over other free fatty acid-activated receptors.

    物理化学性质&存储条件

    分子量 265.70
    分子式 C12H12ClN3O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-((4-chlorophenethyl)amino)pyrimidine-2,4(1H,3H)-dione

    参考文献

    1. Thanigaimalai Pillaiyar, et al. ACS Omega. 2018 Mar 31;3(3):3365-3383.

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