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PSAC inhibitor compound 1

Chemical Structure : PSAC inhibitor compound 1

CAS No.:

PSAC inhibitor compound 1

货号: PC-24699Not For Human Use, Lab Use Only.

PSAC inhibitor compound 1 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.3.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PSAC inhibitor compound 1 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.3.

物理化学性质&存储条件

分子量 437.92
分子式 C24H24ClN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-chloro-N1-isopropyl-N3-(4-(6-methoxypyridin-3-yl)benzyl)isophthalamide

参考文献

1. Molina I, et al. Cell Chem Biol. 2025 May 21:S2451-9456(25)00136-9.

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