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首页-小分子抑制剂&激动剂-TGF-beta/Smad-PKC-PKN2-IN-1
PKN2-IN-1

Chemical Structure : PKN2-IN-1

CAS No.: 942425-34-5

PKN2-IN-1

货号: PC-27816Not For Human Use, Lab Use Only.

PKN2-IN-1 (Compound 8) is a potent, selective and cell penetrant inhibitor of Protein Kinase N2 (PKN2, PRK2) with Ki/IC50 of 8/16 nM, shows 14-fold selectivity over PKN1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PKN2-IN-1 (Compound 8) is a potent, selective and cell penetrant inhibitor of Protein Kinase N2 (PKN2, PRK2) with Ki/IC50 of 8/16 nM, shows 14-fold selectivity over PKN1.

物理化学性质&存储条件

分子量 241.29
分子式 C14H15N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-ethyl-2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one

参考文献

1. Scott F, et al. Bioorg Med Chem Lett. 2022;60:128588.

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