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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Wee1-PKMYT1 inhibitor XH-30
PKMYT1 inhibitor XH-30

Chemical Structure : PKMYT1 inhibitor XH-30

CAS No.: 3077136-87-6

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PKMYT1 inhibitor XH-30

货号: PC-26008Not For Human Use, Lab Use Only.

PKMYT1 inhibitor XH-30 is a highly potent PKMYT1 inhibitor with IC50 of 4.1 nM, suppresses the proliferation of the MDA-MB-231 (P53-mutated TNBC cell line) with IC50 of 1.85 uM, demonstrates antitumor effects in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PKMYT1 inhibitor XH-30 is a highly potent PKMYT1 inhibitor with IC50 of 4.1 nM, suppresses the proliferation of the MDA-MB-231 (P53-mutated TNBC cell line) with IC50 of 1.85 uM, demonstrates antitumor effects in vivo.

物理化学性质&存储条件

分子量 337.38
分子式 C19H19N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-Amino-2-cyclopropyl-7-(3-hydroxy-2,6-dimethylphenyl)benzo[d]oxazole-5-carboxamide

参考文献

1. Jingling Huang, et al. J Med Chem. 2026 Jan 8;69(1):228-249.

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