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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P-glycoprotein (P-gp)-PGP-4008
PGP-4008

Chemical Structure : PGP-4008

CAS No.: 365565-02-2

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PGP-4008 (PGP4008)

货号: PC-26311Not For Human Use, Lab Use Only.

PGP-4008 is a specific inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR), potentiates the cytotoxicity of Pgp substrate drugs (vinblastine, vincristine, and paclitaxel)

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5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PGP-4008 is a specific inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR), potentiates the cytotoxicity of Pgp substrate drugs (vinblastine, vincristine, and paclitaxel)

物理化学性质&存储条件

分子量 393.49
分子式 C26H23N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide

参考文献

1. Lee BD, et al. Oncol Res. 2003;14(1):49-60.

2. Lee BD, et al. J Med Chem. 2004 Mar 11;47(6):1413-22.

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