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首页-小分子抑制剂&激动剂-GPCR-Prostaglandin Receptor-PGN 9856-isopropyl ester
PGN 9856-isopropyl ester

Chemical Structure : PGN 9856-isopropyl ester

CAS No.: 1177429-82-1

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PGN 9856-isopropyl ester (PGN-9856 isopropyl ester)

货号: PC-35836ANot For Human Use, Lab Use Only.

PGN 9856-isopropyl ester is the isopropyl ester, which is a potent, selective prostaglandin EP2 receptor agonist with pKi of > 8.3.

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5 mg ￥2480 In stock
10 mg ￥3980 In stock
25 mg ￥5980 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: 98.65% (HPLC) Select Batch:

生物&药学活性

PGN 9856-isopropyl ester is the isopropyl ester, which is a potent, selective prostaglandin EP2 receptor agonist with pKi of > 8.3.
PGN 9856-isopropyl ester produced profound decreases in monkey intraocular pressure (IOP).
PGN 9856-isopropyl ester appears to possess efficacy and duration of action properties unmatched by currently prescribed anti-glaucoma agents.

物理化学性质&存储条件

分子量 425.43
分子式 C24H21F2NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

isopropyl 2-(3-(3',4-difluoro-[1,1'-biphenyl]-3-carboxamido)phenoxy)acetate

参考文献

1. Woodward DF, et al. J Ocul Pharmacol Ther. 2019 Jun;35(5):265-277.

2. Coleman RA, et al. Br J Pharmacol. 2019 Mar;176(5):687-698.

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