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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-E3 Ubiquitin Ligase-PF-G23
PF-G23

Chemical Structure : PF-G23

CAS No.: 3038775-60-6

PF-G23 (CBL-B inhibitor G23)

货号: PC-25779Not For Human Use, Lab Use Only.

PF-G23 (CBL-B inhibitor G23) is a potent, selective, small molecule inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (CBL-B), shows binding selectivity over C-CBL.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PF-G23 (CBL-B inhibitor G23) is a potent, selective, small molecule inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (CBL-B), shows binding selectivity over C-CBL.

物理化学性质&存储条件

分子量 503.05
分子式 C28H31ClN6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-chloro-6-(3-(5-(4-methyl-4H-1,2,4-triazol-3-yl)spiro[2.3]hexan-5-yl)phenyl)-2-(((1-methylcyclobutyl)amino)methyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

参考文献

1. Patent WO2024105563 A1, Compound G23.

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