PF-4878691 |CAS:532959-63-0 Probechem Biochemicals

Chemical Structure : PF-4878691

CAS No.: 532959-63-0

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PF-4878691 (PF-04878691;PF 4878691;S 32865;3M-852A)

货号: PC-70303Not For Human Use, Lab Use Only.

PF-4878691 (PF-04878691, S32865, 3M-852A) is a selective TLR7 agonist that potently induces IFN-α and IFN-regulated proteins from human PBMC.

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5 mg	￥2280	In stock
10 mg	￥3580	In stock
25 mg	￥5580	In stock
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100 mg		Get quote

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生物&药学活性

PF-4878691 (PF-04878691, S32865, 3M-852A) is a selective TLR7 agonist that potently induces IFN-α and IFN-regulated proteins from human PBMC.
PF 04878691 up-regulates the expression of CD83, CD86, and CD38 in IFN-beta-primed DC but not in immature DC.
PF 04878691 induces significantly less pDC maturation in cells from HIV+ individuals;

物理化学性质&存储条件

分子量	361.46
分子式	C17H23N5O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[4-(4-Amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide

参考文献

1. Severa M, et al. J Immunol. 2007 May 15;178(10):6208-16.

2. Gorden KK, et al. J Immunol. 2006 Dec 1;177(11):8164-70.

3. Martinson JA, et al. Cell Immunol. 2007 Nov-Dec;250(1-2):75-84.

PF-4878691 (PF-04878691;PF 4878691;S 32865;3M-852A)

生物&药学活性

物理化学性质&存储条件

参考文献

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PF-4878691 (PF-04878691;PF 4878691;S 32865;3M-852A)

生物&药学活性

物理化学性质&存储条件

参考文献

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