PF-431396 | FAK/Pyk2 inhibitor | Probechem Biochemicals

Chemical Structure : PF-431396

CAS No.: 717906-29-1

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货号: PC-62800Not For Human Use, Lab Use Only.

PF-431396 is a highly potent, dual PYK2/FAK inhibitor with IC50 of 11 and 2 nM, respectively, promotes osteogenesis of hMSC cultures.

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PF-431396 is a highly potent, dual PYK2/FAK inhibitor with IC50 of 11 and 2 nM, respectively, promotes osteogenesis of hMSC cultures.

分子量	506.504
分子式	C22H21F3N6O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methylmethanesulfonamide

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4. Kanteti R, et al. Cancer Biol Ther. 2018 Jan 5:1-12.