PF-06526290 | Nav1.3 inhibitor | Probechem Biochemicals

Chemical Structure : PF-06526290

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PF-06526290 (PF 06526290)

货号: PC-35154Not For Human Use, Lab Use Only.

PF-06526290 is a potent, selective Nav1.3 inhibitor with IC50 of 5.1 uM, interacts with the Domain 4 voltage sensor domain (D4 VSD and shows no activity for Nav1.7.

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生物&药学活性

PF-06526290 is a potent, selective Nav1.3 inhibitor with IC50 of 5.1 uM, interacts with the Domain 4 voltage sensor domain (D4 VSD and shows no activity for Nav1.7.

物理化学性质&存储条件

分子量	402.49
分子式	C18H18N4O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-benzyl-N-methyl-4-(3-(thiazol-2-yl)ureido)benzenesulfonamide

参考文献

1. Wang L, et al. Br J Pharmacol. 2015 Oct;172(20):4905-18.

2. Wang L, et al. Br J Pharmacol. 2018 May 23. doi: 10.1111/bph.14338.

PF-06526290 (PF 06526290)

生物&药学活性

物理化学性质&存储条件

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PF-06526290 (PF 06526290)

生物&药学活性

物理化学性质&存储条件

参考文献

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