PF-06412562 (PF-2562, CVL-562)

Chemical Structure : PF-06412562

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货号: PC-23107Not For Human Use, Lab Use Only.

PF-06412562 (PF-2562, CVL-562) is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM, Emax 44%, PF-06412562 is a selective D1/D5 dopamine receptor partial agonist.

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生物&药学活性

PF-06412562 (PF-2562, CVL-562) is a potent, selective non-catechol dopamine D1R agonist with Ki of 113 nM and EC50 of 568 nM, Emax 44%, PF-06412562 is a selective D1/D5 dopamine receptor partial agonist.

物理化学性质&存储条件

分子量	331.38
分子式	C19H17N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[4-(4,6-Dimethyl-5-pyrimidinyl)-3-methylphenoxy]-1H-pyrazolo[4,3-c]pyridine

参考文献

1. Sakesh Kumar, et al. Bioorg Chem. 2024 Sep 7:153:107809.

2. Patent US20140128374A1..