Onzotrigine | Nav1.8 inhibitor | Probechem Biochemicals

Chemical Structure : Onzotrigine

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货号: PC-27490Not For Human Use, Lab Use Only.

Onzotrigine (LTG-001) is a potent, selective voltage-gated sodium channel Nav1.8 inhibitor.

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Onzotrigine (LTG-001) is a potent, selective voltage-gated sodium channel Nav1.8 inhibitor.

分子量	484.47
分子式	C21H20F4N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((6-fluoro-2-methylpyridin-3-yl)oxy)-4-methyl-1-(3-(S-methylsulfonimidoyl)phenyl)-5-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide

1. Patent WO2022192487 A2 2022-09-15.

2. Neil Singla, et al. N Engl J Med. 2026 Jul 30;395(5):454-464.