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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-Ondansetron
Ondansetron

Chemical Structure : Ondansetron

CAS No.: 99614-02-5

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Ondansetron (GR 38032, SN 307)

货号: PC-23333Not For Human Use, Lab Use Only.

Ondansetron (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.

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100 mg ￥880 In stock
500 mg ￥1580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ondansetron (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM.
Ondansetron shows negligible agonist or antagonist activity on other 5-HT or non-5-HT receptor-containing tissues.
Ondansetron antagonizes the bradycardic response to 5-HT or 2-methyl-5-HT administered intravenously (i.v.) to anaesthetized animals.

物理化学性质&存储条件

分子量 293.37
分子式 C18H19N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one

参考文献

1. Butler A, et al. Br J Pharmacol. 1988 Jun;94(2):397-412.

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