Obicetrapib (AMG899, TA-8995) | CETP inhibitor | Probechem Biochemicals

Chemical Structure : Obicetrapib

CAS No.: 866399-87-3

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Obicetrapib (AMG-899, AMG899, TA-8995, DEZ-001)

货号: PC-63559Not For Human Use, Lab Use Only.

Obicetrapib (AMG899, TA-8995, DEZ-001) is a potent, selective and orally active cholesteryl ester transfer protein (CETP) inhibitor for treatment of dyslipidaemia.

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5 mg	￥2580	In stock
10 mg	￥3980	In stock
25 mg	￥5980	In stock
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100 mg		Get quote

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生物&药学活性

Obicetrapib (AMG899, TA-8995, DEZ-001) is a potent, selective and orally active cholesteryl ester transfer protein (CETP) inhibitor for treatment of dyslipidaemia.

物理化学性质&存储条件

分子量	722.609
分子式	C32H31F9N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[2-[[3,5-bis(trifluoromethyl)phenyl]methyl-[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]pyrimidin-5-yl]oxybutanoic acid

参考文献

1. Ford J, et al. Br J Clin Pharmacol. 2014 Sep;78(3):498-508.
2. Hovingh GK, et al. Lancet. 2015 Aug 1;386(9992):452-60.
3, Nicholls SJ, et al. Nat Med. 2022 Aug;28(8):1672-1678.

Obicetrapib (AMG-899, AMG899, TA-8995, DEZ-001)

生物&药学活性

物理化学性质&存储条件

参考文献

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Obicetrapib (AMG-899, AMG899, TA-8995, DEZ-001)

生物&药学活性

物理化学性质&存储条件

参考文献

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