OXi8007

Chemical Structure : OXi8007

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货号: PC-25515Not For Human Use, Lab Use Only.

OXi8007 is a vascular disrupting agent and watersoluble phosphate prodrug of OXi8006, inhibits tubulin assembly with IC50 of 1.1 uM, shows cytotoxic against DU-145 cells with GI50 of 36 nM.

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生物&药学活性

OXi8007 is a vascular disrupting agent and watersoluble phosphate prodrug of OXi8006, inhibits tubulin assembly with IC50 of 1.1 uM, shows cytotoxic against DU-145 cells with GI50 of 36 nM.

物理化学性质&存储条件

分子量	587.43
分子式	C26H24NNa2O10P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanone, [6-methoxy-2-[4-methoxy-3-(phosphonooxy)phenyl]-1H-indol-3-yl](3,4,5-trimethoxyphenyl)-, sodium salt (1:2)

参考文献

1. Hadimani MB, et al. J Nat Prod. 2013 Sep 27;76(9):1668-78.

2. Strecker TE, et al. Cancer Lett. 2015 Dec 1;369(1):229-41.

3. Dalal S, et al. Eur J Cancer. 2009 Mar;45(4):713-22.

OXi8007

生物&药学活性

物理化学性质&存储条件

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OXi8007

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