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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-MAPKAPK2 (MK2)-OUN11211
OUN11211

Chemical Structure : OUN11211

CAS No.: 724711-21-1

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OUN11211 (OUN 11211)

货号: PC-38026Not For Human Use, Lab Use Only.

OUN11211 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2, MK2) with IC5 of 8.5 nM.

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10 mg ￥2180 In stock
25 mg ￥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

OUN11211 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2, MK2) with IC5 of 8.5 nM.
OUN11211 demonstrates exceptional selectivity against CDK2, ERK2, JNK2, IKK2, as well as MNK1, MSK1, and MSK2 (IC50=3->100 uM).

物理化学性质&存储条件

分子量 340.39
分子式 C21H16N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,5,6,7-Tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one

参考文献

1. David R Anderson, et al. J Med Chem. 2007 May 31;50(11):2647-54.

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