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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-PARP-OUL245
OUL245

Chemical Structure : OUL245

CAS No.: 1023814-45-0

OUL245 (OUL-245)

货号: PC-25419Not For Human Use, Lab Use Only.

OUL245 is a potent, selective PARP2 inhibitor with IC50 of 44 nM, weakly inhibits multiple poly-ARTs at low μM concentration, does not inhibit mono-ARTs PARP7, PARP11, PARP12, PARP14, and PARP15.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

OUL245 is a potent, selective PARP2 inhibitor with IC50 of 44 nM, weakly inhibits multiple poly-ARTs at low μM concentration, does not inhibit mono-ARTs PARP7, PARP11, PARP12, PARP14, and PARP15.

物理化学性质&存储条件

分子量 191.21
分子式 C8H5N3OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-7-ol

参考文献

1. Murthy S, et al. J Med Chem. 2023 Jan 26;66(2):1301-1320.

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