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首页-小分子抑制剂&激动剂-Epigenetics-Sirtuin -OSS-128167
OSS-128167

Chemical Structure : OSS-128167

CAS No.: 887686-02-4

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OSS-128167 (OSS128167, OSS_128167)

货号: PC-63273Not For Human Use, Lab Use Only.

OSS-128167 (OSS_128167) is a novel selective, cell permeable SIRT6 inhibitor with IC50 of 89, 1578 and 751 uM for SIRT6, SIRT1 and SIRT2, respectively.

规格 价格 库存 数量
5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

OSS-128167 (OSS_128167) is a novel selective, cell permeable SIRT6 inhibitor with IC50 of 89, 1578 and 751 uM for SIRT6, SIRT1 and SIRT2, respectively.
OSS-128167 increases H3K9 acetylation and GLUT-1 expression in treated cells.

物理化学性质&存储条件

分子量 366.329
分子式 C19H14N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid

参考文献

1. Parenti MD, et al. J Med Chem. 2014 Jun 12;57(11):4796-804.

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