OAT-2068 |CAS: 2221950-65-6 Probechem Biochemicals

Chemical Structure : OAT-2068

CAS No.: 2221950-65-6

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OAT-2068 (OAT2068)

货号: PC-62539Not For Human Use, Lab Use Only.

OAT-2068 is a potent, selective, orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1) with IC50 of 29 nM, 143-fold selectivity over mAMCase.

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10 mg	￥5480	In stock
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生物&药学活性

OAT-2068 is a potent, selective, orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1) with IC50 of 29 nM, 143-fold selectivity over mAMCase.
OAT-2068 exhibits excellent pharmacokinetic profile and is an ideal and unique tool for studying the role of CHIT1 in biological models.

物理化学性质&存储条件

分子量	446.04
分子式	C23H36ClN7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-((2S,5S)-2-(4-chlorobenzyl)-4-isobutyl-5-methylpiperazin-1-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine

参考文献

1. Mazur M, et al. Bioorg Med Chem Lett. 2017 Dec 22. pii: S0960-894X(17)31221-0.

OAT-2068 (OAT2068)

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物理化学性质&存储条件

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OAT-2068 (OAT2068)

生物&药学活性

物理化学性质&存储条件

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