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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-JAK-Nomelcitinib
Nomelcitinib

Chemical Structure : Nomelcitinib

CAS No.: 2794195-73-4

Nomelcitinib (D-2570, D2570)

货号: PC-26345Not For Human Use, Lab Use Only.

Nomelcitinib (D-2570) is a potent, selective tyrosine kinase 2 (TYK2) inhibitor, selectively binds to the JH2 domain of TYK2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Nomelcitinib (D-2570) is a potent, selective tyrosine kinase 2 (TYK2) inhibitor, selectively binds to the JH2 domain of TYK2.

物理化学性质&存储条件

分子量 427.88
分子式 C16H14D3ClN6O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Pyridazinecarboxamide, 4-[[5-chloro-3-(methylsulfonyl)-2-pyridinyl]amino]-6-[(cyclopropylcarbonyl)amino]-N-(methyl-d3)-

参考文献

1. Patent WO2022135430 A1 2022-06-30.

2. Zhang J, et al. J Am Acad Dermatol. 2026 Jan;94(1):143-150.

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