Nesvacumab |CAS:1296818-77-3 Probechem Biochemicals

Chemical Structure : Nesvacumab

CAS No.: 1296818-77-3

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Nesvacumab (Anti-human Ang-2 mAb, human IgG1-Kappa; REGN910)

货号: PC-Ab1101Not For Human Use, Lab Use Only.

Nesvacumab (REGN910) is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand vascular growth factor called angiopoietin2 (Ang2) with high affinity (Kd=24 pM), but shows no binding to Ang1..

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1 mg	￥3580	In stock
5 mg	￥7580	In stock
10 mg	￥12800	In stock
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生物&药学活性

物理化学性质&存储条件

分子量
分子式	Human IgG1-Kappa
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES	Nesvacumab; REGN910; REGN-910; Anti-human Angiopoietin-2; Anti-human Ang-2; 1296818-77-3; Tie2 receptor antagonist

参考文献

1. 1, Wu FT, et al. Sci Rep. 2016 Nov 14;6:36694. 2, Papadopoulos KP, et al. Clin Cancer Res. 2016 Mar 15;22(6):1348-55. 3, Hussain RM, et al. Expert Opin Investig Drugs. 2019 Oct;28(10):861-869.

Nesvacumab (Anti-human Ang-2 mAb, human IgG1-Kappa; REGN910)

生物&药学活性

物理化学性质&存储条件

参考文献

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Nesvacumab (Anti-human Ang-2 mAb, human IgG1-Kappa; REGN910)

生物&药学活性

物理化学性质&存储条件

参考文献

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