Nek2 inhibitor 66 (NCL-00017509)

Chemical Structure : Nek2 inhibitor 66

CAS No.: 1507367-00-1

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货号: PC-20311Not For Human Use, Lab Use Only.

Nek2 inhibitor 66 (NCL-00017509) is a potent, selective and irreversible inhibitor of Nek2 with IC50 of 62 nM, exhibits growth inhibitory activity in the SKBR3 cell line with GI50 of 2.2 uM.

规格	价格	库存
1 mg	￥1880	In stock
5 mg	￥3580	In stock
10 mg	￥5480	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Nek2 inhibitor 66 (NCL-00017509) is a potent, selective and irreversible inhibitor of Nek2 with IC50 of 62 nM, exhibits growth inhibitory activity in the SKBR3 cell line with GI50 of 2.2 uM.
Nek2 inhibitor 66 (5-10 uM) reduced C-Nap1 phosphorylation in U2OS cells.

物理化学性质&存储条件

分子量	292.30
分子式	C15H12N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-((6-ethynyl-9H-purin-2-yl)amino)phenyl)acetamide

参考文献

1. Christopher J Matheson, et al. RSC Med Chem. 2020 May 22;11(6):707-731.