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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-Nafadotride
Nafadotride

Chemical Structure : Nafadotride

CAS No.: 149649-22-9

Nafadotride

货号: PC-28316Not For Human Use, Lab Use Only.

Nafadotride is a selective dopamine D3 receptor (D3R) antagonist, displays a high affinity for dopamine D2 and D3 receptors, but a low affinity for doparnine D1 and D4.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Nafadotride is a selective dopamine D3 receptor (D3R) antagonist, displays a high affinity for dopamine D2 and D3 receptors, but a low affinity for doparnine D1 and D4.

物理化学性质&存储条件

分子量 365.48
分子式 C22H27N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide

参考文献

1. Sautel F, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1239-46.

2. Parsons LH, et al. J Neurochem. 1996 Sep;67(3):1078-89.

3. Levant B, et al. Neuropsychopharmacology. 1999 Aug;21(2):304-11.

4. Bordet R, et al. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3363-7.

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