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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Chloride Channel-NSC602247
NSC602247

Chemical Structure : NSC602247

CAS No.: 131555-87-8

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NSC602247

货号: PC-26735Not For Human Use, Lab Use Only.

NSC602247 is a small molecule inhibitor of human chloride intracellular channel 1 (HsCLIC1), binds to HsCLIC1 with micromolar affinity (6 uM), NSC602247 impairs HT29 cell growth and inhibits HsCLIC1 membrane translocation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NSC602247 is a small molecule inhibitor of human chloride intracellular channel 1 (HsCLIC1), binds to HsCLIC1 with micromolar affinity (6 uM), NSC602247 impairs HT29 cell growth and inhibits HsCLIC1 membrane translocation.

物理化学性质&存储条件

分子量 308.34
分子式 C17H16N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4,4'-((6-methylpyrimidine-2,4-diyl)bis(azanediyl))diphenol

参考文献

1. Shobhan Kuila, et al. J Biol Chem. 2026 May 6:113113.

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