NSC405020 (NSC 405020)

Chemical Structure : NSC405020

CAS No.: 7497-07-6

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货号: PC-28744Not For Human Use, Lab Use Only.

NSC405020 (NSC 405020) is a selective matrix metalloproteinase-14 (MMP14, MT1-MMP) inhibitor, interacts with the hemopexin (PEX) domain of MMP14, represses tumor growth and causes a fibrotic, ΔPEX-like tumor phenotype in vivo.

规格	价格	库存
25 mg	￥780	In stock
50 mg	￥1180	In stock
100 mg	￥1880	In stock
250 mg		Get quote

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生物&药学活性

NSC405020 (NSC 405020) is a selective matrix metalloproteinase-14 (MMP14, MT1-MMP) inhibitor, interacts with the hemopexin (PEX) domain of MMP14, represses tumor growth and causes a fibrotic, ΔPEX-like tumor phenotype in vivo.

物理化学性质&存储条件

分子量	260.16
分子式	C12H15Cl2NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,4-Dichloro-N-(pentan-2-yl)benzamide

参考文献

1. Thang ND, et al. PLoS One. 2014 May 9;9(5):e96945.

2. Kittaka M, et al. J Bone Miner Res. 2018 Jan;33(1):167-181.

3. Albert G Remacle, et al. Cancer Res. 2012 May 1;72(9):2339-49.