 
                Chemical Structure : NSC305787
CAS No.: 785718-37-8
货号: PC-45560Not For Human Use, Lab Use Only.
NSC305787 is a small molecule inhibitor of Ezrin with Kd of 5.85 uM.
| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 5 mg | ¥2580 | In stock | |
| 10 mg | ¥3980 | In stock | |
| 25 mg | ¥5980 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote | 
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	NSC305787 is a small molecule inhibitor of Ezrin with Kd of 5.85 uM.
	NSC305787 inhibits ezrin phosphorylation, ezrin-actin interaction and ezrin-mediated motility of osteosarcoma (OS) cells in culture.
	NSC305787 inhibits lung metastasis of ezrin-sensitive cells in mice; also inhibits SHIP-1 and SHIP-2.
| 分子量 | 445.4245 | |
| 分子式 | C25H30Cl2N2O | |
| 外观性状 | Solid | |
| 储存条件 | 
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| Solubility | 10 mM in DMSO | |
| Chemical Name/SMILES | 4-Quinolinemethanol, 6,8-dichloro-α-2-piperidinyl-2-tricyclo[3.3.1.13,7]dec-1-yl- | |
1. Bulut G, et al. Oncogene. 2012 Jan 19;31(3):269-81.
2. Russo CM, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5344-8.
3. Çelik H, et al. J Biol Chem. 2016 Jun 17;291(25):13257-70.
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