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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-NSC207895
NSC207895

Chemical Structure : NSC207895

CAS No.: 58131-57-0

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NSC207895 (XI-006)

货号: PC-26088Not For Human Use, Lab Use Only.

NSC207895 (XI-006) is a small-molecule inhibitor of MDMX (MDM4) and p53 activator, activates p53 and induces apoptosis, inhibits MDMX expression in cancer cells.

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10 mg ￥1280 In stock
25 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NSC207895 (XI-006) is a small-molecule inhibitor of MDMX (MDM4) and p53 activator, activates p53 and induces apoptosis, inhibits MDMX expression in cancer cells.

物理化学性质&存储条件

分子量 279.26
分子式 C11H13N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,1,3-Benzoxadiazole, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide

参考文献

1. Woodfield SE, et al. Sci Rep. 2021 Feb 3;11(1):2967.

2. Wang H, et al. Mol Cancer Ther. 2011 Jan;10(1):69-79.

3. Pishas KI, et al. Sci Rep. 2015 Jun 22;5:11465.

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