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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-NSC158011
NSC158011

Chemical Structure : NSC158011

CAS No.: 201015-15-8

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NSC158011 (NSC-158011)

货号: PC-28469Not For Human Use, Lab Use Only.

NSC158011 (NSC-158011) is a small molecule inhibitor of P. falciparum phosphoethanolamine N-methyltransferase (PfPMT), inhibits phosphatidylcholine (PC) biosynthesis, shows strong gametocytocidal activity.

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10 mg ￥1280 In stock
25 mg ￥1980 In stock
50 mg ￥3280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NSC158011 (NSC-158011) is a small molecule inhibitor of P. falciparum phosphoethanolamine N-methyltransferase (PfPMT), inhibits phosphatidylcholine (PC) biosynthesis, shows strong gametocytocidal activity.

物理化学性质&存储条件

分子量 309.45
分子式 C18H15NS2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(Naphthalen-1-yl)-2-(phenylthio)ethanethioamide

参考文献

1. Frieman M, et al. PLoS One. 2011;6(12):e28479.

2. Bobenchik AM, et al. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18262-7.

3. Garg A, et al. Sci Rep. 2015 Mar 12;5:9064.

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