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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Microtubule/Tubulin-NSC-639829
NSC-639829

Chemical Structure : NSC-639829

CAS No.: 134742-19-1

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NSC-639829 (NSC639829)

货号: PC-60870Not For Human Use, Lab Use Only.

NSC-639829 is a potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NSC-639829 is a potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization.

    物理化学性质&存储条件

    分子量 470.327
    分子式 C21H20BrN5O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-(dimethylamino)benzamide

    参考文献

    1. Abdel-Aziz W, et al. Invest New Drugs. 2003 Nov;21(4):421-8.

    2. Jain A, et al. AAPS PharmSciTech. 2003 Oct 15;4(4):E52.

    3. Balcer-Kubiczek EK, et al. Cancer Chemother Pharmacol. 2007 May;59(6):781-7.

    4. Hallur G, et al. J Med Chem. 2006 Apr 6;49(7):2357-60.

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