NP-G2-029

Chemical Structure : NP-G2-029

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货号: PC-24546Not For Human Use, Lab Use Only.

Fascin inhibitor G2 (NP-G2-029) is a specific small molecule inhibitor of Fascin (FSCN1) with IC50 of 0.19 uM in F-actin-bundling assay.

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生物&药学活性

Fascin inhibitor G2 (NP-G2-029) is a specific small molecule inhibitor of Fascin (FSCN1) with IC50 of 0.19 uM in F-actin-bundling assay, decreases the migration of mouse and human breast tumor cells. NP-G2-029 decreases the actin-bundling activity of fascin and tumor cell migration

物理化学性质&存储条件

分子量	400.36
分子式	C20H15F3N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-methyl-N-(1-(4-(trifluoromethyl)benzyl)-1H-indazol-3-yl)isoxazole-5-carboxamide

参考文献

1. Lirui Lin, et al. Front Chem. 2021 Oct 7:9:719949.

2. Gong R, et al. Nat Struct Mol Biol. 2025 Jan 20. doi: 10.1038/s41594-024-01477-2.

3. Huang J, et al. J Mol Biol. 2018 Apr 27;430(9):1324-1335.

NP-G2-029

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物理化学性质&存储条件

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NP-G2-029

生物&药学活性

物理化学性质&存储条件

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