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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Deubiquitinase (DUB)-NK192
NK192

Chemical Structure : NK192

CAS No.: 1959552-23-8

NK192 (NK-192)

货号: PC-26806Not For Human Use, Lab Use Only.

NK192 is a potent, selective USP7 inhibitor with IC50 of 20 nM, shows proteome-wide specificity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NK192 is a potent, selective USP7 inhibitor with IC50 of 20 nM, shows proteome-wide specificity.

物理化学性质&存储条件

分子量 489.55
分子式 C27H28FN5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-(4-fluorophenyl)-5-((4-hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

参考文献

1. Klink N, et al. Nat Commun. 2026 May 13;17(1):4331.

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