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首页-抗体药物偶连体和PROTACs-E3 Ligase Ligand-NJH-2-030
NJH-2-030

Chemical Structure : NJH-2-030

CAS No.: 2709040-02-6

NJH-2-030 (EN106 derivative 3)

货号: PC-38766Not For Human Use, Lab Use Only.

EN106 derivative 3 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

EN106 derivative 3 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation.

物理化学性质&存储条件

分子量 373.83
分子式 C19H20ClN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Chloro-N-(2-cyanoethyl)-N-(4-(hex-5-ynoyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)acetamide

参考文献

1. Nathaniel J. Henning, et al. J. Am. Chem. Soc. 2022, 144, 2, 701–708.

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