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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein -NCGC00029283
NCGC00029283

Chemical Structure : NCGC00029283

CAS No.: 714240-31-0

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NCGC00029283

货号: PC-26950Not For Human Use, Lab Use Only.

NCGC00029283 is a specific small molecule inhibitor of Werner Syndrome helicase-nuclease (WRN) with IC50 of 2.3 uM, 12.5 uM and 3.4 uM for WRN, BLM and FANCJ.

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5 mg ￥1780 In stock
10 mg ￥2780 In stock
25 mg ￥4880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NCGC00029283 is a specific small molecule inhibitor of Werner Syndrome helicase-nuclease (WRN) with IC50 of 2.3 uM, 12.5 uM and 3.4 uM for WRN, BLM and FANCJ.

物理化学性质&存储条件

分子量 337.31
分子式 C18H12FN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(5-(4-Fluorophenyl)-1,2,4-oxadiazol-3-yl)-6-methoxyquinolin-2(1H)-one

参考文献

1. Joshua A Sommers, et al. PLoS One. 2019 Jan 9;14(1):e0210525.

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