NA-014 (NA014)

Chemical Structure : NA-014

CAS No.: 3041127-59-4

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货号: PC-28283Not For Human Use, Lab Use Only.

NA-014 is a potent, selective positive allosteric modulator (PAM) of excitatory amino acid transporter 2 (EAAT2, rodent homologue glutamate transporter-1, GLT-1) with EC50 of 3.0 nM, is inactive against EAAT1 and EAAT3.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3580	In stock
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100 mg		Get quote

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NA-014 is a potent, selective positive allosteric modulator (PAM) of excitatory amino acid transporter 2 (EAAT2, rodent homologue glutamate transporter-1, GLT-1) with EC50 of 3.0 nM, is inactive against EAAT1 and EAAT3.

物理化学性质&存储条件

分子量	380.46
分子式	C22H25FN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-Cyanophenyl)-N-(4-fluorophenethyl)-2-(4-methylpiperazin-1-yl)acetamide

参考文献

1. Fontana ACK, et al. J Med Chem. 2024 Apr 25;67(8):6119-6143.

2. Reeb KL, et al. Eur J Pharmacol. 2024 Dec 5;984:177017.

NA-014 (NA014)

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NA-014 (NA014)

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