MtbIMPDH2 inhibitor P41

Chemical Structure : MtbIMPDH2 inhibitor P41

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货号: PC-28184Not For Human Use, Lab Use Only.

MtbIMPDH2 inhibitor P41 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, MtbIMPDH) with Ki app of 17 nM for MtbIMPDH2ΔCBS, displays significant activity against Mtb strain H37Rv in minimal BSA-free medium with MIC of 5 uM.

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100 mg		Get quote

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生物&药学活性

MtbIMPDH2 inhibitor P41 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB2, MtbIMPDH2) with Ki app of 17 nM for MtbIMPDH2ΔCBS, displays significant activity against Mtb strain H37Rv in minimal BSA-free medium with MIC of 5 uM.

物理化学性质&存储条件

分子量	399.92
分子式	C22H26ClN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-chloro-N,N-dimethyl-5-(3-(2-(3-(prop-1-en-2-yl)phenyl)propan-2-yl)ureido)benzamide

参考文献

1. Makowska-Grzyska M, et al. PLoS One. 2015 Oct 6;10(10):e0138976.