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Mtb GuaB-IN-2

Chemical Structure : Mtb GuaB-IN-2

CAS No.: 3096055-86-3

Mtb GuaB-IN-2

货号: PC-28181Not For Human Use, Lab Use Only.

Mtb GuaB-IN-2 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, IMPDH) with IC50 of 0.2 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Mtb GuaB-IN-2 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, IMPDH) with IC50 of 0.2 nM.

物理化学性质&存储条件

分子量 412.44
分子式 C22H22F2N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2H-Pyrano[3,4-c]quinoline, 9-[(1R)-1-[1-[3-(difluoromethyl)bicyclo[1.1.1]pent-1-yl]-1H-1,2,3-triazol-4-yl]ethoxy]-1,4-dihydro-

参考文献

1. Sabnis RW. ACS Med Chem Lett. 2025 Oct 30;16(11):2204-2205.

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